Neuroscience@NIH > Faculty

Senior Investigator

Anand Swaroop, Ph.D.

Building 6 Room 338

6 Center Drive MSC0610
Bethesda MD 20814

Office: (301) 435-5754

swaroopa@nei.nih.gov

Dr. Swaroop obtained his Ph.D. at the Indian Institute of Science in Bangalore, India, and postdoctoral training at Yale University. He joined the University of Michigan in 1990 as assistant professor in Ophthalmology and Human Genetics. He became full professor in 2000 and Harold F. Falls Collegiate Professor in 2003. In September 2007, Dr. Swaroop joined the National Eye Institute as Senior Investigator to establish a new program in retinal development and knowledge-based treatment paradigms for retinal degenerative diseases. He has received several honors, including the Board of Director' s award from The Foundation Fighting Blindness, the Harrington Senior Scientific Award from Research to Prevent Blindness, and Distinguished Faculty Lectureship Award from the Univ of Michigan Medical School. The goal of Dr. Swaroop' s group is to develop novel treatment modalities for blinding retinal diseases based on a fundamental understanding of genetic defects and/or biological pathways underlying differentiation, homeostasis, aging and disease pathogenesis.

Dr. Swaroop is the Lab Chief of the Neurobiology Neurodegeneration and Repair Laboratory: https://www.nei.nih.gov/research/research-labs-and-branches/neurobiology-neurodegeneration-repair-laboratory

Members of the Neurobiology, Neurodegeneration and Repair Laboratory are listed here: https://www.nei.nih.gov/research/research-labs-and-branches/neurobiology-neurodegeneration-repair-laboratory and members of the Retinal Development, Genetics and Therapy section are listed here: https://www.nei.nih.gov/research/research-labs-and-branches/neurobiology-neurodegeneration-repair-laboratory/retinal-development-genetics-and-therapy-section

1) Ratnapriya R, Sosina OA, Starostik MR, Kwicklis M, Kapphahn RJ, Fritsche LG, Walton A, Arvanitis M, Gieser L, Pietraszkiewicz A, Montezuma SR, Chew EY, Battle A, Abecasis GR, Ferrington DA, Chatterjee N, Swaroop A (2019)

Retinal transcriptome and eQTL analyses identify genes associated with age-related macular degeneration
Nat Genet, 51(4), 606-610

2) Brooks MJ, Chen HY, Kelley RA, Mondal AK, Nagashima K, De Val N, Li T, Chaitankar V, Swaroop A. (2019)

Improved retinal organoid differentiation by modulating signaling pathways revealed by comparative transcriptome analyses with development in vivo
Stem Cell Reports, 13(5), 891-905

3) Corso-Diaz X, Jaeger C, Chaitankar V, Swaroop A (2018)

Epigenetic control of gene regulation during development and disease
Prog Retin Eye Res, 65:1-27

4) Shimada H, Lu Q, Insinna-Kettenhofen C, Nagashima K, English MA, Semler EM, Mahgerefteh J, Cideciyan AV, Li T, Brooks BP, Gunay-Aygun M, Jacobson SG, Cogliati T, Westlake CJ, Swaroop A (2017)

In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations
Cell Rep, 20(2):384-396

5) Kim J-W, Yang H-J, Oel AP, Brooks MJ, Jia L, Li W, Allison WT, Swaroop A (2016)

Recruitment of rod photoreceptors from short-wavelength-sensitive cones during the evolution of nocturnal vision in mammals
Dev Cell, 37(6):520-532

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