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Senior Investigator

Susan M. Resnick, Ph.D.

Laboratory of Behavioral Neuroscience

Building 251 Room Suite 100
Bayview Boulevard
Baltimore MD 21224
Office: 410-558-8618

Dr. Resnick received her Ph.D. in Differential Psychology and Behavioral Genetics from the University of Minnesota and completed a postdoctoral fellowship in Neuropsychology and Neuroimaging at the University of Pennsylvania. She was Research Assistant Professor of Psychology in Psychiatry at the University of Pennsylvania prior to joining the Laboratory of Personality and Cognition (Now the Laboratory of Behavioral Neuroscience), NIA in 1992.

Dr. Resnick studies brain-behavior associations in health and disease and is currently the principal investigator of the brain imaging component of the Baltimore Longitudinal Study of Aging (BLSA). This longitudinal neuroimaging study focuses on early structural and physiological brain changes that may be predictors of memory and cognitive change in older individuals. Through this study and others in the BLSA, she has also been examining the hormonal modulation of age-associated cognitive and brain changes. Based on findings from these studies, she initiated the Women's Health Initiative Study of Cognitive Aging (WHISCA), an ancillary study to the Women's Health Initiative Memory Study (WHIMS) and the WHI randomized trials of the effects of hormone therapy.

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  • 1) Zhou H, Liao J, Aloor J, Nie H, Wilson BC, Fessler MB, Gao HM, Hong JS (2013)
  • CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses
  • J Immunol, 190(1), 115-25
  • 2) Gao HM, Zhou H, Zhang F, Wilson BC, Kam W, Hong JS (2011)
  • HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration
  • J Neurosci, 31(3), 1081-92
  • 3) Block ML, Zecca L, Hong JS (2007)
  • Microglia-mediated neurotoxicity: uncovering the molecular mechanisms.
  • Nat Rev Neurosci, 8(1), 57-69
  • 4) Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS (2004)
  • NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
  • J Biol Chem, 279(2), 1415-21
  • 5) Liu B, Hong JS (2003)
  • Role of microglia in inflammation-mediated neurodegenerative diseases: mechanisms and strategies for therapeutic intervention
  • J Pharmacol Exp Ther, 304(1), 1-7
View Pubmed Publication